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diagnosis differential hepatitisb injury transaminitis treatment dili phases cancer causes chemistry common cvid disease drug druginduced epidemiology function gastroenterology hematology
Hepatitis B Management in Cancer DOI: 10.1200/JCO.20.01757 #HepatitisB #HBV #HepBV #Management #Cancer #oncology #hepatology #algorithm
Hepatitis B Management ... JCO.20.01757 #HepatitisB ... #HBV #HepBV #Management ... Cancer #oncology #hepatology ... #algorithm
Chronic Hepatitis B - Diagnosis and Management Algorithm • Who to treat: Essentially treat the pts with
Chronic Hepatitis ... HAV immunity; Liver ... Chronic Hepatitis ... #HepatitisB #HBV ... #Hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... normal - Infection (EBV ... 5-10x normal - Chronic ... #Injury #hepatology ... #LFTs #transaminitis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... , HBV, HCV, HEV, ... Hepatic ischaemia ... hepatitis fibrosis ... #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Tests (LFTs) - ... Cirrhosis • Chronic ... Viral Hepatitis ... injury) • Ischemic ... Differential #Diagnosis #hepatology
Hepatitis B Phases and Treatment Phase 1 - HBeAg+ Chronic Infection Phase 2 - HBeAg+ Chronic Hepatitis Phase 3
Hepatitis B Phases ... Seroconv Occult HBV ... #HBV #HepBV #Phases ... #Treatment #Management ... #diagnosis #hepatology
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... mg/dL) or acute liver ... #HepBV #HBV #Treatment ... #Indications #management ... #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
• Infections: Hepatitis ... • Vascular: Ischemic ... Differential #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Hepatitis B Disease Progression Timeline • > 90% of infected children progress to chronic disease (<5%
Hepatitis B Disease ... develop Liver Cancer ... developing cirrhosis #HepatitisB ... Timeline #Prognosis #hepatology ... #Epidemiology #HepB
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Drugs/Toxins • Ischemia ... • Alcoholic hepatitis ... • Others #LFTs ... #Hepatology #LiverEnzymes
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