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diagnosis differential injury lfts transaminitis treatment aclf acute alcoholic autoimmune causes cirrhosis common cvid dili druginduced failure gastroenterology hematology hepatitisb
Chronic Hepatitis B - Diagnosis and Management Algorithm • Who to treat: Essentially treat the pts with
Chronic Hepatitis ... HAV immunity; Liver ... Chronic Hepatitis ... #HepatitisB #HBV ... #Hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... Hepatic ischaemia ... e.g. ascites), Chronic ... hepatitis fibrosis ... #hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... normal - Infection (EBV ... 5-10x normal - Chronic ... #Patterns #Liver ... #Injury #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... (AAH) Drug-Induced ... ) Viral Hepatitis ... #ACLF #Acute #Chronic ... #Cirrhosis #Hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
• Infections: Hepatitis ... • Vascular: Ischemic ... Differential #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... > 2 • NASH, Chronic ... injury: > 3 • Chronic ... differential #diagnosis #algorithm ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Drugs/Toxins • Ischemia ... • Drugs • AIH ... • Alcoholic hepatitis ... Others #LFTs #Hepatology
Alcoholic Hepatitis - Management Algorithm 1. Severity assessed not only by MDF (>32) but also by MELD
- Management Algorithm ... survival in severe AH ... can be bridge to Liver ... #Management #Algorithm ... #treatment #hepatology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
disease to acute liver ... - Symptoms of chronic ... hepatocellular pattern of liver ... (eg Viral) Management ... #Management #Hepatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Autoimmunity • Chronic ... disease • Liver ... diseases and hepatitis ... Malignancies • Chronic ... #diagnosis #management
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