18 results
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... for alternative causes ... , HBV, HCV, HEV, ... Hepatic ischaemia ... #Algorithm #hepatology
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
Chronic Hepatitis ... HAV immunity; Liver ... Chronic Hepatitis ... #HepatitisB #HBV ... #Hepatology
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... injury (INR > 2 ... mg/dL) or acute liver ... #HepBV #HBV #Treatment ... Indications #management #hepatology
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
• Infectious: HAV ... , HCV, HEV, EBV, ... Trauma: Shock liver ... Differential #Diagnosis #causes ... #hepatology
Hepatitis B Phases and Treatment
Phase 1 - HBeAg+ Chronic Infection
Phase 2 - HBeAg+ Chronic Hepatitis
Phase 3
and Treatment ... Seroconv Occult HBV ... #HBV #HepBV #Phases ... #Treatment #Management ... #diagnosis #hepatology
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... Injury Transaminase ... normal - Infection (EBV ... 5-10x normal - Chronic ... #Injury #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Vascular Causes ... : HAV, HBV, HCV, ... HEV, EBV, HSV, ... #injury #hepatitis ... #hepatology
Hepatitis B Disease Progression Timeline
 • > 90% of infected children progress to chronic disease (<5%
HBV-infected individuals ... develop Liver Cancer ... of chronic HBV-infected ... #Epidemiology #HepB ... #HBV
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... , CMV, HSV • Toxic ... #Acute #algorithm ... #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Injuryliver ... CMV, HSV, VZV ... • Vascular: Ischemic ... #Diagnosis #hepatology ... #algorithm #Transaminitis