35 results
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
- Ischemic Hepatitis ... , Toxic Hepatitis ... #Injury #hepatology ... #LFTs #transaminitis ... #differential #diagnosis
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
Chronic Hepatitis ... serologic evidence of hepatitis ... Chronic Hepatitis ... .2018.3795 #Chronic #HepatitisB ... #HBV #Algorithm
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
Trauma: Shock liver ... • Autoimmune hepatitis ... See Updated Schema ... Transaminases #hepatitis ... #causes #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Tests (LFTs) - ... Chronic Viral Hepatitis ... • Acute Viral Hepatitis ... injury) • Ischemic ... #hepatology #transaminitis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Algorithm DILI ... Hepatic ischaemia ... ascites), Chronic hepatitis ... • Autoimmune hepatitis ... #Algorithm #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
• Infections: Hepatitis ... • Vascular: Ischemic ... #hepatology #algorithm ... Transaminitis #LFTs ... #hepatitis
Hepatitis Virus Screening Algorithm
 - Hepatitis A Virus Antibody, IgM
 - Hepatitis B Virus Core Antibody,
Hepatitis Virus ... - Hepatitis A ... Antibody, IgM - Hepatitis ... Antibody, IgM - Hepatitis ... #diagnosis #hepatology
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... infection with severe liver ... mg/dL) or acute liver ... failure #HepatitisB ... Indications #management #hepatology
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
hepatitis - Acute ... injury - Viral Hepatitis ... - Autoimmune hepatitis ... #Differential #Hepatology ... #Diagnosis
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... Drugs/Toxins • Ischemia ... • Alcoholic hepatitis ... • Others #LFTs ... #Hepatology #LiverEnzymes