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diagnosis differential injury causes chronic hepatitisb transaminitis aclf aih alcoholic cirrhosis druginduced elevated failure gastroenterology hepatocellular hepbv indications lfts transaminases
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
, HBV, HCV, HEV, ... Hepatic ischaemia ... dechallenge • Acute ... hepatitis #DILI ... #hepatology
Elevated Transaminases / Transaminitis - Differential Diagnosis • Infectious: HAV, HCV, HEV, EBV, HSV, CMV •
Trauma: Shock liver ... obstruction syndrome • Autoimmune ... : DILI, Tylenol, ... See Updated Schema ... Diagnosis #causes #hepatology
Chronic Hepatitis B - Diagnosis and Management Algorithm • Who to treat: Essentially treat the pts with
Diagnosis and Management ... Algorithm • ... HAV immunity; Liver ... #HBV #Algorithm ... #Treatment #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Differential Diagnosis Algorithm ... : Autoimmune hepatitis ... • Iatrogenic: DILI ... #hepatology
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... liver failure ... #HBV #Treatment ... #Indications #management ... #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... Injury (DILI) ... Viral Hepatitis ... Failure #Cirrhosis #Hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... C, A, E, B, D, EBV ... Other: NAFLD, Autoimmune ... hepatitis, Acute ... #algorithm #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
• Vascular: Ischemic ... Other: NAFLD, Autoimmune ... Differential #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Alcoholic Hepatitis - Management Algorithm Assess Eligibility for Treatment: - Maddrey Discriminant Function ≥ (or possibly MELD
- Management Algorithm ... diseases including HBV ... HCV, DILI, HCC, ... #Management #Algorithm ... #hepatology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
Autoimmune Hepatitis ... subclinical disease to acute ... liver failure ... regarding need for treatment ... #Hepatology
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