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diagnosis differential lfts injury causes abnormal chemistry chronic dili druginduced function hepatitisb hepatocellular interpretation liverenzymes liverfunctiontests management patterns rvalue tests
Elevated Transaminases / Transaminitis - Differential Diagnosis • Infectious: HAV, HCV, HEV, EBV, HSV, CMV •
Elevated Transaminases ... / Transaminitis ... Trauma: Shock liver ... See Updated Schema ... Diagnosis #causes #hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... normal - Infection (EBV ... #Patterns #Liver ... #Injury #hepatology ... #LFTs #transaminitis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Elevated Liver Function ... Chronic Viral Hepatitis ... injury) • Ischemic ... Differential #Diagnosis #hepatology ... #transaminitis
Chronic Hepatitis B - Diagnosis and Management Algorithm • Who to treat: Essentially treat the pts with
and Management Algorithm ... HAV immunity; Liver ... #HBV #Algorithm ... Diagnosis #Management #Treatment ... #Hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... non-essential drug/HDS treatments ... Hepatic ischaemia ... • Autoimmune hepatitis ... #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
• Infections: Hepatitis ... • Vascular: Ischemic ... Differential #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... for Transaminitis ... Drugs, Viral, Ischemia ... kwburak #LFTs #Elevated ... #hepatology #LiverFunctionTests
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... specificity to elevated ... #injury #hepatitis ... differential #diagnosis #algorithm ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Differential Diagnosis Algorithm ... Drugs/Toxins • Ischemia ... • Alcoholic hepatitis ... Others #LFTs #Hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Check Acute viral hepatitis ... serologies, HCV ... specificity to elevated ... #differential #Hepatology ... #transaminitis
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