7 results
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... - Ischemic Hepatitis ... LouLectures #Patterns ... Liver #Injury #hepatology ... #LFTs #transaminitis
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... Drugs/Toxins • Ischemia ... • Autoimmune ... • Alcoholic hepatitis ... • Others #LFTs
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Drugs, Viral, Ischemia ... Burak @kwburak #LFTs ... #Elevated #Abnormal ... #diagnosis #hepatology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
Autoimmune Hepatitis ... hepatocellular pattern ... IgG typically elevated ... upper limit of normal ... #Hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
• Vascular: Ischemic ... Other: NAFLD, Autoimmune ... Differential #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Differential Diagnosis Algorithm ... Celiac disease • Autoimmune ... : Autoimmune hepatitis ... specificity to elevated ... #hepatology
Possible approach to empiric anticoagulation in COVID-19

Is D-dimer above '"1,000-2,000 ng/ml?
Contraindication to anticoagulation?
Check fibrinogen level and/or
or elevated Hypo-coagulable ... pattern (rare, ... anticoagulation #COVID19 #management ... #schema #criticalcare ... #algorithm #SARSCOV2