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diagnosis differential transaminitis liver injury abnormal aih anticoagulation autoimmune causes coronavirus covid19 criticalcare empiric function hepatocellular liverenzymes liverfunctiontests sarscov2 schema
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... > 50x normal - Ischemic ... LouLectures #Patterns ... Liver #Injury #hepatology ... #LFTs #transaminitis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Elevated Liver Function ... Tests (LFTs) - ... Chronic Viral Hepatitis ... liver injury) • Ischemic ... Differential #Diagnosis #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Drugs/Toxins • Ischemia ... • Alcoholic hepatitis ... • Others #LFTs ... #Hepatology #LiverEnzymes
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Hepatocellular Pattern ... Drugs, Viral, Ischemia ... Burak @kwburak #LFTs ... #Elevated #Abnormal ... #diagnosis #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
• Infections: Hepatitis ... • Vascular: Ischemic ... Differential #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
hepatocellular pattern ... though cholestatic pattern ... IgG typically elevated ... (eg Viral) Management ... #Hepatology
Possible approach to empiric anticoagulation in COVID-19 Is D-dimer above '"1,000-2,000 ng/ml? Contraindication to anticoagulation? Check fibrinogen level and/or
hyper-coagulable pattern ... level is normal or elevated ... anticoagulation #COVID19 #management ... #schema #criticalcare ... #algorithm #SARSCOV2
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