23 results
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver Injury ... 20x normal - Acute ... #hepatology #LFTs ... transaminitis #differential ... #diagnosis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
) - Differential ... Hepatopathy • Acute ... Drug-induced liver injury ... ) • Ischemic Hepatopathy ... Diagnosis #hepatology
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
Liver Injury ... - Ichemic hepatitis ... Drug-Induced liver injury ... #Causes #Differential ... #Hepatology #Diagnosis
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Differential Diagnosis ... • Vascular: Ischemic ... Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Differential Diagnosis of Acute Kidney Injury 

#Diagnosis #Nephrology #AKI #Acute #KidneyInjury #Causes #Differential #Workup #Algorithm #Ddxof
Differential Diagnosis ... of Acute Kidney ... Injury #Diagnosis ... #Workup #Algorithm ... #Ddxof
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Diagnosis Algorithm ... Drugs/Toxins • Ischemia ... • Alcoholic hepatitis ... • Others #LFTs ... Diagnosis #Algorithm
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Diagnosis Hepatocellular ... #Differential # ... #Acute #algorithm ... #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... Production: • Albumin ... liver #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Algorithm DILI ... disease, Hepatic ischaemia ... dechallenge • Acute ... #Diagnosis #Algorithm ... #hepatology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Acute Kidney Injury ... (AKI) - Differential ... Diagnosis Framework ... Other • ATN: Ischemia ... #causes #algorithm