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liver causes transaminitis aki chemistry dehydrogenase dili druginduced elevated emesis function hepatocellular interpretation kidney laboratory lactate liverenzymes liverinjury nausea nephrology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver Injury ... 20x normal - Acute ... #hepatology #LFTs ... transaminitis #differential ... #diagnosis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
) - Differential ... Hepatopathy • Acute ... Drug-induced liver injury ... ) • Ischemic Hepatopathy ... Diagnosis #hepatology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
) - Differential ... Diagnosis Framework ... hepatitis • Ischemic ... hepatitis • Acute ... hepatitis (ALT-to-LDH
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
Liver Injury ... - Ichemic hepatitis ... Drug-Induced liver injury ... #Causes #Differential ... #Hepatology #Diagnosis
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Differential Diagnosis ... • Vascular: Ischemic ... Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Diagnosis Algorithm ... Drugs/Toxins • Ischemia ... • Alcoholic hepatitis ... • Others #LFTs ... Diagnosis #Algorithm
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Diagnosis Hepatocellular ... #Differential # ... #Acute #algorithm ... #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... muscle, Kidneys • LDH ... liver #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Diagnosis Algorithm ... #hepatitis #differential ... #diagnosis #algorithm ... #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Algorithm DILI ... disease, Hepatic ischaemia ... dechallenge • Acute ... #Diagnosis #Algorithm ... #hepatology
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