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differential causes hepatitis gastroenterology lfts transaminitis acidosis aclf acute alcoholic cardiology chronic cirrhosis classification drug druginduced effusion elevation endocarditis failure
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Injury (DILI) ... #differential #Diagnosis ... #algorithm #gastroenterology ... #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Injury (DILI) - ... Algorithm DILI ... disease, Hepatic ischaemia ... #Injury #Diagnosis ... #Algorithm #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
- Differential Diagnosis ... (>1000): • DILI ... injury) • Ischemic ... #Differential #Diagnosis ... #hepatology #transaminitis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... - Differential Diagnosis ... Algorithm Vascular ... #differential #diagnosis ... #algorithm #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Injury (DILI) ... Hepatitis Procedures Management ... Failure #Cirrhosis #Hepatology ... gastroenterology #management ... #diagnosis
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Diagnosis Framework ... : Liver Injury ... • Vascular: Ischemic ... #Diagnosis #hepatology ... #algorithm #Transaminitis
Causes of Seizures - Differential Diagnosis Algorithm Unprovoked - Epilepsy: • Focal: Simple, Complex • Generalized: Absence,
- Differential Diagnosis ... Algorithm Unprovoked ... Traumatic brain injury ... Encephalitis, Brain Abscess ... , Liver failure,
Causes of Pleural Effusion - Differential Diagnosis Algorithm Transudate - Hydrostatic • Congestive heart failure • Constrictive
- Differential Diagnosis ... Algorithm Transudate ... • Subphrenic abscess ... • Postcardiac injury ... #Algorithm #Hepatology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
- Differential Diagnosis ... or renal injury ... assessment - assess ... 30mmHg) - Severe anemia ... Injury: • Reduced
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
Septic Emboli Cause Injury ... Early embolic/ischemic ... Differential Diagnosis ... Leukocytosis, anemia ... #management #cardiology
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