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differential causes gastroenterology lfts transaminitis acidosis aclf acute chronic cirrhosis classification druginduced elevation failure function hepatitis hepatocellular idiosyncratic induced lactate
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Liver Injury (DILI ... #Liver #Injury # ... #algorithm #gastroenterology ... #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... Injury (DILI) - ... Algorithm DILI ... #Injury #Diagnosis ... #Algorithm #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
- Differential Diagnosis ... (>1000): • DILI ... (Drug-induced liver ... injury) • Ischemic ... #hepatology #transaminitis
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Hepatitis (AAH) Drug-Induced ... Liver Injury (DILI ... Failure #Cirrhosis #Hepatology ... gastroenterology #management ... #diagnosis
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
: Liver Injury ... valproate, azoles), Drugs ... • Vascular: Ischemic ... #Diagnosis #hepatology ... #algorithm #Transaminitis
Causes of Seizures - Differential Diagnosis Algorithm Unprovoked - Epilepsy: • Focal: Simple, Complex • Generalized: Absence,
Algorithm Unprovoked ... , Recreational drugs ... Traumatic brain injury ... Encephalitis, Brain Abscess ... , Liver failure,
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
or renal injury ... circulation If drugs ... 30mmHg) - Severe anemia ... Alcohol • Type B2: Drugs ... Injury: • Reduced
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