8 results
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... #Injury #Idiosyncratic ... #differential #Diagnosis ... #algorithm #gastroenterology ... #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Diagnosis Framework ... : Liver Injury ... • Vascular: Ischemic ... #Diagnosis #hepatology ... #algorithm #Transaminitis
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
- Differential Diagnosis ... RBCs, muscle, liver ... • Hemolytic Anemias ... Sarcoidosis Idiosyncratic ... #differential #diagnosis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis ... Algorithm DILI ... disease, Hepatic ischaemia ... #Injury #Diagnosis ... #Algorithm #hepatology
Causes of Seizures - Differential Diagnosis Algorithm
Unprovoked - Epilepsy:
 • Focal: Simple, Complex
 • Generalized: Absence,
- Differential Diagnosis ... Algorithm Unprovoked ... Traumatic brain injury ... Encephalitis, Brain Abscess ... , Liver failure,
Causes of Pleural Effusion - Differential Diagnosis Algorithm
Transudate - Hydrostatic
 • Congestive heart failure
 • Constrictive
- Differential Diagnosis ... Algorithm Transudate ... • Subphrenic abscess ... • Postcardiac injury ... #Algorithm #Hepatology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
- Differential Diagnosis ... or renal injury ... assessment - assess ... 30mmHg) - Severe anemia ... Injury: • Reduced
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Septic Emboli Cause Injury ... Early embolic/ischemic ... Differential Diagnosis ... Leukocytosis, anemia ... #management #cardiology