13 results
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... Injury • AST/ALT elevation ... #Enzymes #LFTs ... Transaminitis #diagnosis #differential ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential ... Drugs/Toxins • Ischemia ... • Others #LFTs ... #Hepatology #LiverEnzymes
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Elevated Liver Function ... Tests (LFTs) - ... Differential Diagnosis ... injury) • Ischemic ... Diagnosis #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
- Differential ... Diagnosis Algorithm ... ALP: - Enzymes ... #Differential # ... #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Drugs, Viral, Ischemia ... Burak @kwburak #LFTs ... #Elevated #Abnormal
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... specificity to elevated ... Enzyme Elevation ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Mild jaundice, Elevated ... to 10-20-fold elevation ... Liver enzymes, ... Disease #Pregnancy #hepatology ... hepatitis #comparison #differential
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... • Vascular: Ischemic ... #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
elevation and clinical ... #LFTs #Abnormal ... #Algorithm #Hepatology ... #Liver #Enzymes ... #Differential #
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... a cytoplasmic enzyme ... RBCs, muscle, liver ... Idiosyncratic LDH Elevation ... #differential #