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diagnosis causes lfts transaminitis injury elevated abnormal acute albumin alcoholic aloc altered ascites chemistry comatose dehydrogenase druginduced evaluation fever function
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Tests (LFTs) - Differential ... Chronic Viral Hepatitis ... (>1000): • DILI ... injury) • Ischemic ... #Diagnosis #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... Hepatocellular: Viral infections ... disease, Hepatic ischaemia ... #Diagnosis #Algorithm ... #hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... 10-20x normal - Infection ... #Patterns #Liver ... #Injury #hepatology ... transaminitis #differential
Elevated Transaminases / Transaminitis - Differential Diagnosis • Infectious: HAV, HCV, HEV, EBV, HSV, CMV •
Diagnosis • Infectious ... Trauma: Shock liver ... • Iatrogenic: DILI ... See Updated Schema ... Diagnosis #causes #hepatology
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Diagnosis Algorithm ... Non-Malignant • Fatty Liver ... Pericarditis Infectious ... Cholangitis • Abscess ... #Causes #Hepatology
Fever in Returning Travelers from Tropical Regions - Frequent Differential Diagnoses Medical History: • Skin exposure to
Regions - Frequent Differential ... Jaundice (and/or elevation ... abscess • Diarrhea ... abscess, visceral ... Returning #Traveler #differential
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Diagnosis Algorithm ... Injury: • Infectious ... • Iatrogenic: DILI ... #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Diagnosis: • Infections ... : Hepatitis A/B/ ... • Vascular: Ischemic ... #Diagnosis #hepatology ... #algorithm #Transaminitis
Liver Mass - Differential Diagnosis Algorithm Cystic: • Benign - Simple: Simple
Liver Mass - Differential ... Diagnosis Algorithm ... Benign - Infectious ... : Abscess ... #Causes #Hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Injury - Differential ... Parenchyma • Infectious ... , TPN • Infectious ... Causes #Acute #algorithm ... #hepatology
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