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diagnosis differential hematology aptt bilirubin bleeding bruising coagulation hyperbilirubinemia pt congenital conjugated hemochromatosis hemostasis hepatitis inherited injury lfts liverenzymes management
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Early liver disease ... Reduced liver synthesis ... Jcortesizaguirr #Abnormal ... #differential #hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Diagnosis for a Prolonged ... Causes include : ... • Reduced liver ... amyloidosis #Abnormal ... #differential #hematology
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm 1. Definition: T.bili elevation + >20% conjugated 2. Obtain RUQ
non-ICU vs ICU causes ... MRCP, ERCP, liver ... Hyperbilirubinemia #direct ... #gastroenterology ... #hepatology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Differential Diagnosis Algorithm ... Destruction • Abnormal ... Iatrogenic) • Liver ... #Causes #Hematology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Drugs/Toxins • Ischemia ... disease US — Normal ... Others #LFTs #Hepatology ... #Causes
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
dabigatran, argatroban, direct ... the PT remains prolonged ... discern these causes ... Anticoagulants (warfarin, direct ... Differential #Diagnosis #Hematology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. Step 1: In the patient with
Algorithm regarding ... <45% and SF is normal ... hemochromatosis #algorithm ... diagnosis #management #hepatology ... #gastroenterology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... Vascular Causes ... Half-life: 1 week • Direct ... function may be abnormal ... #hepatology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
of about 30% of normal ... of hemolysis or liver ... and stress may cause ... Congenital #bilirubin #hepatology ... #diagnosis #gastroenterology
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