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differential hematology management injury lfts anemia transaminitis acute bleeding hepatitis polycythemia workup ascites biliary bilirubin bruising cirrhosis classification coagulation elevated
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... disease 6-9 mo ... #differential #Diagnosis ... #algorithm #gastroenterology ... #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Algorithm DILI ... for alternative causes ... disease, Hepatic ... ischaemia, Autoantibody ... #Algorithm #hepatology
Elevated Transaminases / Transaminitis - Differential Diagnosis • Infectious: HAV, HCV, HEV, EBV, HSV, CMV •
Trauma: Shock liver ... Metabolic: Wilson Disease ... • Iatrogenic: DILI ... See Updated Schema ... #causes #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
disease, liver ... Injury (DILI) ... Failure #Cirrhosis #Hepatology ... #gastroenterology ... #management #diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Algorithm Vascular ... Causes of Acute ... • Iatrogenic: DILI ... function may be abnormal ... #algorithm #hepatology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Algorithm Normal ... Deficiency - Abnormal ... #Algorithm #Causes ... #Hematology
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
Causes of Severe ... - Ichemic hepatitis ... hepatitis - Wilson disease ... #Differential #Hepatology ... #Diagnosis
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Algorithm Low ... Renal Disease, Liver ... #Algorithm #Causes ... #Hematology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Drugs/Toxins • Ischemia ... • Cholestatic disease ... Others #LFTs #Hepatology ... #Algorithm #Causes
Liver Mass - Differential Diagnosis Algorithm Benign Cystic • Cyst • Polycystic Liver Disease • Caroli's
Diagnosis Algorithm ... Disease • Caroli's ... #Mass #Hepatology ... #Differential #Diagnosis ... #Algorithm #Causes
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