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diagnosis differential injury lfts transaminitis dili chemistry drug druginduced failure function fungal hbv hemochromatosis hepatitis hepatitisb idiosyncratic induced infections infectiousdiseases
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... those with CLD (± cirrhosis ... #Acute #Chronic ... #Cirrhosis #Hepatology ... #gastroenterology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... > 20x normal - Acute ... CMV), Alcoholic cirrhosis ... 5-10x normal - Chronic ... #Injury #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
• NAFLD • Cirrhosis ... • Chronic Viral ... Hepatopathy • Acute ... injury) • Ischemic ... Differential #Diagnosis #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... presentation • Chronic ... #gastroenterology ... #algorithm #gastroenterology ... #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... disease, Hepatic ischaemia ... dechallenge • Acute ... or chronic atypical ... #hepatology
Chronic Hepatitis B - Diagnosis and Management Algorithm • Who to treat: Essentially treat the pts with
Diagnosis and Management ... Algorithm • ... viremia or have cirrhosis ... #Diagnosis #Management ... #Treatment #Hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
ALF): • Liver ... > 2 • NASH, Chronic ... hepatitis: < 1 • Cirrhosis ... injury: > 3 • Chronic ... #differential #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Differential Diagnosis Algorithm ... > 2 • NASH, Chronic ... hepatitis: < 1 • Cirrhosis ... #hepatology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. Step 1: In the patient with
Algorithm regarding ... Patients with cirrhosis ... hemochromatosis #algorithm ... #diagnosis #management ... #hepatology #gastroenterology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
presents with acute ... , with ensuing ischemia ... Mississippi and Ohio River ... , neutropenia, cirrhosis ... Fungal #Diagnosis #Management
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