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diagnosis differential management causes lfts injury transaminitis treatment albumin saag aflp chronic gastroenterology gradient hbv hepatitisb indications obstetrics pregnancy aclf
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... - Ischemic Hepatitis ... - Acute Viral Hepatitis ... CMV), Alcoholic cirrhosis ... #Injury #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
• NAFLD • Cirrhosis ... Hepatopathy • Acute ... Viral Hepatitis ... injury) • Ischemic ... Differential #Diagnosis #hepatology
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
Causes of Severe Acute ... Liver Injury ... - Ichemic hepatitis ... - Drug-Induced liver ... #Differential #Hepatology
Diagnosis of ascites according to the serum ascites albumin gradient (SAAG) SAAG ≥ 1.1: - Ascitic protein
Diagnosis of ascites ... protein ≤ 2.5 g/dL: Cirrhosis ... syndrome, Massive liver ... albumin #gradient #hepatology ... differential #diagnosis #algorithm
Ascites - Differential Diagnosis Chronic liver disease (cirrhosis or chronic hepatitis) - 80% Underlying malignancy - 10% Congestive heart
Ascites - Differential ... Diagnosis Chronic liver ... disease (cirrhosis ... or chronic hepatitis ... Differential #Diagnosis #hepatology
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis High albumin gradient (>1.1 g/dl): - Cirrhosis - Alcoholic
- Alcoholic hepatitis ... - Massive liver ... Veno-occlusive disease - Acute ... associated with bowel ischemia ... Differential #Diagnosis #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... those with CLD (± cirrhosis ... (DILI) Viral Hepatitis ... #Failure #Cirrhosis ... #Hepatology #gastroenterology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Drugs/Toxins • Ischemia ... • Alcoholic hepatitis ... Infiltrative • Cirrhosis ... Others #LFTs #Hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... disease, Hepatic ischaemia ... dechallenge • Acute ... disorder (e.g. ascites ... #hepatology
Causes of Ascites Normal Peritoneum Portal hypertension (SAAG > 1.1 g/dL) 1. Hepatic congestionl
Normal Peritoneum ... - Cirrhosis ... - Alcoholic hepatitis ... fibrosis - Acute ... #differential #hepatology
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