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diagnosis differential causes injury management transaminitis ascites gastroenterology hbv hepatitisb dili disease saag treatment abnormal aclf aih albumin arthritis autoimmune
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
20x normal - Acute ... CMV), Alcoholic cirrhosis ... 5-10x normal - Chronic ... #Injury #hepatology ... #LFTs #transaminitis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
• NAFLD • Cirrhosis ... • Chronic Viral ... Hepatopathy • Acute ... injury) • Ischemic ... Differential #Diagnosis #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... those with CLD (± cirrhosis ... #Chronic #Liver ... #Failure #Cirrhosis ... #Hepatology #gastroenterology
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
Causes of Severe Acute ... Liver Injury ... - Ichemic hepatitis ... - Drug-Induced liver ... #Differential #Hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Drugs/Toxins • Ischemia ... • Alcoholic hepatitis ... • Others #LFTs ... #Hepatology #LiverEnzymes
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
Inflammation - Hepatitis ... 15 percent) - Hepatitis ... Nonalcoholic fatty liver ... heart failure (chronic ... #Differential #Hepatology
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 Ascites - Differential Diagnosis Chronic liver disease (cirrhosis or chronic hepatitis) - 80% Underlying malignancy - 10% Congestive heart
Differential Diagnosis Chronic ... liver disease ( ... cirrhosis or chronic ... hepatitis) - 80% ... Differential #Diagnosis #hepatology
Chronic Hepatitis B - Diagnosis and Management Algorithm • Who to treat: Essentially treat the pts with
Chronic Hepatitis ... and Management Algorithm ... viremia or have cirrhosis ... Chronic Hepatitis ... Management #Treatment #Hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
• Infections: Hepatitis ... • Vascular: Ischemic ... Differential #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... disease, Hepatic ischaemia ... dechallenge • Acute ... hepatitis fibrosis ... #hepatology
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