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diagnosis differential hematology causes injury lfts mcv atlas dili druginduced elevatedmcv hepatitis hepatocellular key liverenzymes macrocytosis morphologic morphology rbc transaminitis
Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
Anemia • 812 ... Hypothyroid • Liver ... Disease • Alcohol ... #diagnosis #algorithm ... #hematology #workup
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... Infections Macrocytic ... Non-megaloblastic: Liver ... disease, Alcoholism ... #MCV #Algorithm
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Lead poisoning • Macrocytic ... , Liver diseases ... Malignant tumors, Acute ... , Liver diseases ... #differential #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Differential Diagnosis Algorithm ... • Drugs Oval Macrocytes ... • Pancreatic Disease ... Disease #Macrocytic ... #Causes #Hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
chronic kidney disease ... , Acute blood loss ... MCV - >96fL - "Macrocytic ... : Alcohol use, Liver ... disease (independent
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Drugs/Toxins • Ischemia ... ALT < 5x ULN • NAFLD ... • Cholestatic disease ... Others #LFTs #Hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Antitrypsin • Other: NAFLD ... Syndrome, Celiac Disease ... , Infiltrative Disease ... #algorithm #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
• Vascular: Ischemic ... antitrypsin • Other: NAFLD ... HELLP, Celiac disease ... Differential #Diagnosis #hepatology ... #algorithm #Transaminitis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... disease, Hepatic ... ischaemia, Autoantibody ... dechallenge • Acute ... #hepatology
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