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diagnosis differential lfts hepatitis abnormal causes chemistry dili druginduced elevated function hepatocellular interpretation liverfunctiontests patterns rvalue tests
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
100-500): • NAFLD ... Hepatopathy • Acute ... injury) • Ischemic ... Differential #Diagnosis #hepatology ... #transaminitis
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... > 20x normal - Acute ... normal - Hemolysis, NASH ... #Injury #hepatology ... #LFTs #transaminitis
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... for Transaminitis ... Drugs, Viral, Ischemia ... Wilson's, HH, NAFLD ... #hepatology #LiverFunctionTests
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Injury → liver ... • Vascular: Ischemic ... antitrypsin • Other: NAFLD ... #Diagnosis #hepatology ... #algorithm #Transaminitis
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... Antitrypsin • Other: NAFLD ... #Injury #Differential ... #algorithm #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Mixed - Check Acute ... injury < 26 weeks ... disease: > 2 • NASH ... #differential #Hepatology ... #transaminitis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Differential Diagnosis Algorithm ... Liver Injury: ... disease: > 2 • NASH ... #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Injury (DILI) - ... Stepwise Diagnosis Algorithm ... disease, Hepatic ischaemia ... dechallenge • Acute ... #Algorithm #hepatology
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