9 results
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Drugs, Viral, Ischemia ... Burak @kwburak #LFTs ... #Elevated #Abnormal ... #diagnosis #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Elevated Liver Function ... Tests (LFTs) - ... 100-500): • NAFLD ... injury) • Ischemic ... #hepatology #transaminitis
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... Algorithm Severe ... Drugs/Toxins • Ischemia ... • Others #LFTs ... #Hepatology #LiverEnzymes
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... - Hemolysis, NASH ... #Injury #hepatology ... #LFTs #transaminitis ... #differential #diagnosis
NAFLD Diagnosis Algorithm
Two-step diagnostic strategy for NAFLD
1st step: 
  - Clinical biomarkers, scoring systems- FIB4,
NAFLD Diagnosis ... #NonAlcoholic #Fatty ... #NAFLD #Diagnosis ... #Algorithm #hepatology ... #NASH
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
- Differential Diagnosis ... • Vascular: Ischemic ... antitrypsin • Other: NAFLD ... #hepatology #algorithm ... Transaminitis #LFTs
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... tests algorithm ... non-alcoholic fatty ... #LFTs #Abnormal ... #Algorithm #Hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
specificity to elevated ... Production: • Albumin ... disease: > 2 • NASH ... #chemistry #diagnosis ... #differential #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... Algorithm Vascular ... specificity to elevated ... disease: > 2 • NASH ... #algorithm #hepatology