13 results
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Tests (LFTs) - ... 100-500): • NAFLD ... (>1000): • DILI ... injury) • Ischemic ... Differential #Diagnosis #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Injury (DILI) ... Chronic - ongoing ↑ LFTs ... disease 6-9 mo ... gastroenterology #algorithm ... gastroenterology #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Injuryliver ... • Vascular: Ischemic ... #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Injury (DILI) - ... Stepwise Diagnosis Algorithm ... disease, Hepatic ... ischaemia, Autoantibody ... #Algorithm #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... Drugs/Toxins • Ischemia ... • Cholestatic disease ... • Others #LFTs ... #Hepatology #LiverEnzymes
Non-alcoholic fatty liver disease algorithm.
 
For those patients with NAFLD or liver disease of unknown aetiology,
liver disease algorithm ... or liver disease ... liver disease; ... #NAFLD #algorithm ... Referral #Management #Hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Drugs, Viral, Ischemia ... Wilson's, HH, NAFLD ... Burak @kwburak #LFTs ... #diagnosis #hepatology
NAFLD Diagnosis Algorithm
Two-step diagnostic strategy for NAFLD
1st step: 
  - Clinical biomarkers, scoring systems- FIB4,
Algorithm Two-step ... inspection of liver ... #NonAlcoholic #Fatty ... #Liver #Disease ... #Algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Differential Diagnosis Algorithm ... • Iatrogenic: DILI ... differential #diagnosis #algorithm ... #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Injury - Differential ... Antitrypsin • Other: NAFLD ... #Injury #Differential ... Causes #Acute #algorithm ... #hepatology