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diagnosis differential causes nonalcoholic transaminitis abnormal acute dili management arterial drug druginduced elevated embolism enzymes fattyliver function gastroenterology hematology hepatitis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
100-500): • NAFLD ... • DILI (Drug-induced ... liver injury) ... • Ischemic Hepatopathy ... Differential #Diagnosis #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Injury → liver ... • Vascular: Ischemic ... #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Drugs/Toxins • Ischemia ... • Cholestatic disease ... • Others #LFTs ... #Hepatology #LiverEnzymes
Non-alcoholic fatty liver disease algorithm. For those patients with NAFLD or liver disease of unknown aetiology,
liver disease algorithm ... or liver disease ... liver disease; ... #NAFLD #algorithm ... Referral #Management #Hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Liver Injury (DILI ... Chronic - ongoing ↑ LFTs ... disease 6-9 mo ... #Liver #Injury ... gastroenterology #algorithm
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
Injury - Ichemic ... obstruction - Drug-Induced ... liver injury ... hepatitis - Wilson disease ... #Differential #Hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Drugs, Viral, Ischemia ... Wilson's, HH, NAFLD ... Burak @kwburak #LFTs ... #diagnosis #hepatology
NAFLD Diagnosis Algorithm Two-step diagnostic strategy for NAFLD 1st step: - Clinical biomarkers, scoring systems- FIB4,
Algorithm Two-step ... inspection of liver ... #NonAlcoholic #Fatty ... #Liver #Disease ... #Algorithm #hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Injury - Differential ... Antitrypsin • Other: NAFLD ... #Injury #Differential ... Causes #Acute #algorithm ... #hepatology
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Non-Malignant • Fatty ... Liver • Cysts ... Hemochromatosis • Wilson's Disease ... Hepatitis • Drug Induced ... #Causes #Hepatology
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