14 results
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver Injury ... Infection (EBV/CMV), Alcoholic ... AST:ALT > 2.5 - Alcoholic ... Patterns #Liver #Injury ... #hepatology #LFTs
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Elevated Liver Function ... Tests (LFTs) - ... Drug-induced liver injury ... ) • Ischemic Hepatopathy ... Differential #Diagnosis #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... Drugs/Toxins • Ischemia ... hepatitis • Drugs ... • Others #LFTs ... #Hepatology #LiverEnzymes
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Drugs (MDMA), Alcohol ... • Vascular: Ischemic ... Differential #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Differential Diagnosis Algorithm ... Drugs, Viral, Ischemia ... Burak @kwburak #LFTs ... #Elevated #Abnormal ... #diagnosis #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... non-essential drug/HDS treatments ... HEV, EBV, CMV), Alcohol-related ... disease, Hepatic ischaemia ... #hepatology
Alcoholic Hepatitis - Summary Overview
- Epidemiology
- Pathophysiology
- Clinical Features
- Labs
- Diagnosis
- Differential Diagnosis
- Treatment

Sarah Onorato @sonorato11

#Alcoholic
Alcoholic Hepatitis ... Pathophysiology - Clinical ... Differential Diagnosis - Treatment ... #Hepatitis #hepatology ... #diagnosis #algorithm
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... specificity to elevated ... ALT Ratios: • Alcoholic ... #differential #Hepatology ... transaminitis #LFTs
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Failure (ACLF) Clinical ... months without treatment ... Failure Infections Alcohol-Associated ... Drug-Induced Liver Injury ... Failure #Cirrhosis #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Differential Diagnosis Algorithm ... specificity to elevated ... ALT Ratios: • Alcoholic ... #diagnosis #algorithm ... #hepatology