10 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... cytopenias (usually anemia ... only curative treatment ... #treatment #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... autoantibodies that will cause ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management ... #treatment
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... Behcets #disease #Syndrome ... #Treatment #management ... #pharmacology # ... rheumatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... and petechiae Causes ... Treatment: ... #oncology #hematology ... #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... AKI, acute limb ischemia ... organ damage • Treatment ... TLS #diagnosis #management ... #hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
sinus thrombosis, VTE ... retinal tears, Ischemia ... Arthritis, AS Treatment ... #diagnosis #management ... signs #symptoms #rheumatology
Recurrent Polymorphic VT/Torsades de Pointes - Management Algorithm
Drugs that prolong QT interval:
 • Class 1a (quinidine,
Recurrent Polymorphic VT ... Algorithm Drugs ... Congenital long QT Syndrome ... Hypocalcemia (rarely) Treatment ... #Algorithm
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
acute coronary syndrome ... the determined cause ... #differential #algorithm ... #management #cardiology ... icu #clinical #pharmacology
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
Cholesterol emboli syndrome ... Septic emboli cause ... Early embolic/ischemic ... Leukocytosis, anemia ... hematuria, + RF Treatment
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... Adenocarcinoma Treatment ... lubricants • Pharmacologic ... #Rheumatology # ... Diagnosis #Management