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diagnosis management causes differential rhabdomyolysis hematology leukostasis lysis summary tumor tumorlysis
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS Laboratory TLS: • Uric
(TLS) and Treatment ... 8.0 mg/dL • Potassium ... : • AKI (defined ... hydroxide • Hyperkalemia ... #management #oncology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Acidosis, Cell Lysis (TLS ... /crush injury, ischemia ... , RTA Type IV, AI ... reabsorption) Workup ... #potassium #nephrology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
fever - ACS, AKI ... , acute limb ischemia ... values: Elevated K, ... hydration - Hyperkalemia ... #TLS #diagnosis
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
HIV, Influenza, TSS ... + myoglobin AKI ... perfusion → renal ischemia ... Monitor potassium ... #nephrology
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
HIV, Influenza, TSS ... Dermatomyositis) AKI ... decreased renal renal ischemia ... Monitor potassium ... Dialysis for severe hyperkalemia
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