7 results
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
(TLS) and Treatment ... 8.0 mg/dL • Potassium ... : • AKI (defined ... gluconate #TumorLysis ... #Syndrome #TLS
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Distributive Shock, HRS, Hypercalcemia ... Abdominal Compartment Syndrome ... Other • ATN: Ischemia ... Differential #Diagnosis #nephrology ... #causes #algorithm
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
HIV, Influenza, TSS ... + myoglobin AKI ... perfusion → renal ischemia ... Monitor potassium ... #nephrology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
HIV, Influenza, TSS ... Dermatomyositis) AKI ... decreased renal renal ischemia ... Monitor potassium ... Dialysis for severe hyperkalemia
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
fever - ACS, AKI ... , acute limb ischemia ... leukapheresis - TLS ... hydration - Hyperkalemia ... #TLS #diagnosis
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Acidosis, Cell Lysis (TLS ... /crush injury, ischemia ... , RTA Type IV, AI ... reabsorption) Workup ... #potassium #nephrology
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
which all carry treatment ... hormones that work ... for Refeeding Syndrome ... provided the starting potassium ... #differential #algorithm