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hematology differential management leukemia syndromes angina chestpain classification emergencies hemeonc hodgkins lymphocytic lymphoma mds mitralvalve mitralvalveregurgitation mr myelodysplasia myelodysplastic oncologic
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
ALL Symptoms: ... • Tumor lysis syndrome ... ) CLL Symptoms: ... Leukemia #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... with no early symptoms ... Diagnosis: • ... microglobulin Treatment ... #workup #oncology
ISCHEMIA Trial - Management Algorithm for patients with Stable Angina Stress Test -> ? +moderate or severe
Management Algorithm ... with a stable symptom ... acute coronary syndrome ... Angina #ChestPain #Diagnosis ... #Cardiology #EBM
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
hematology for workup ... , including BM Bx ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... • Infections: Chronic
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... age 70 years Symptoms ... Marrow Failure • Chronic ... #diagnosis #hematology ... #oncology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
full infectious work-up ... days → add fungal work-up ... interventional radiology ... ± tocilizumab; call ... #HemeOnc #Diagnosis
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal Syndromes ... EGPA) • Digital ischemia ... mononeuritis multiplex WORKUP ... or serologies + symptoms ... #management #treatment
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... Presentation: Systemic Symptoms ... CRP GCA (Giant Cell ... • Progressive symptoms ... Eosinophilia, asthma, chronic
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... ingestion • B symptoms ... Hodgkin Lymphoma Workup ... Hodgkin Lymphoma Treatment ... classification #hematology #oncology
Mitral valve regurgitation is the heart’s version of a plot twist — just when you think
degenerative disease, ischemic ... work. ... not forget the symptoms ... Diagnosis by echocardiography ... detective story, and treatment
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