11 results
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Abnormal PT and/or aPTT ... Early liver disease ... Reduced liver synthesis ... Causes #diagnosis #differential ... #hematology #coagulation
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... the PT and the aPTT ... • Reduced liver ... Causes #diagnosis #differential ... #hematology #coagulation
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Bleeding / Bruising - Differential ... Rare • Drugs (e.g ... • Steroids • Vasculitis ... Iatrogenic) • Liver ... Algorithm #Causes #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... cases: INR/PT, aPTT ... (liver disease, ... bypass), LFT (liver ... Causes #Workup #hematology
Ulcerative Blastomycosis Skin Lesion
57 asymptomatic M from Indiana nonpruritic, painless, progressive skin lesion lower back x
Lives in an old ... heaped up borders); differential ... Blastomycosis #SkinRash ... #dermatology #clinical
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
of Hemostasis - Differential ... suggests liver ... integrity == • Vasculitis ... Bruising #Hemostasis #Differential ... #Diagnosis #Hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Autoimmune diseases • Clinical ... the spleen or liver ... involvement Differential ... Lymphomas • Other hematologic ... #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Nephrotic Syndrome, Ischemic ... Liver, IBD • ... 19 - PNH - Vasculitis ... pathophysiology #hematology ... #differential #
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
fever syndromes Clinical ... Fever is the main clinical ... thrombocytopenia • Liver ... Hypofibrinogenemia • ↑ PT ↑ PTT ... Diagnosis #Management #Hematology
Vancomycin induced Leukocytoclastic Vasculitis (LCV) of the Hand
70 M vertebral osteomyelitis on vancomycin and cefepime for
Leukocytoclastic Vasculitis ... Differential for ... HSP, urticarial vasculitis ... #LCV #Hand #skinrash ... #dermatology #clinical