12 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential ... Diagnosis and Workup ... selected cases: INR/PT ... ., SLE), anti-phospholipid ... #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Destruction • Abnormal ... Sequestration Disordered ... Rare • Drugs (e.g ... Iatrogenic) • Liver ... Algorithm #Causes #Hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Erythematosus (SLE ... ) Clinical Manifestations ... , Seizure disorders ... Lumbar Puncture, EEG
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Nail Disorders secondary ... Abnormality • SLE ... halt nail growth (e.g ... discoloration) • Liver ... #Differential #
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... • Reduced liver ... associated with systemic ... amyloidosis #Abnormal ... #hematology #coagulation
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... Early liver disease ... associated with systemic ... Causes #diagnosis #differential ... #hematology #coagulation
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... Syndrome: • Clinical ... - (Ischemia, ... (e.g. systemic ... erythematosus (SLE
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... permanent alopecia Differential ... . hematologic) ... lymphoproliferative syndrome Clinical
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Fever is the main clinical ... erythematosus [SLE ... thrombocytopenia • Liver ... Hypofibrinogenemia • ↑ PT ... Diagnosis #Management #Hematology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... affected joint • Systemic ... profile, including liver ... metabolic or endocrine disorders ... ANA and RF (if clinical