34 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... : ischemic pain ... #Pain #SickleCell ... #Disease #differential ... diagnosis #causes #hematology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint ... Pain Rash ... #joint #pain #skin ... #rashes #differential ... #diagnosis #rheumatology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
Disease: • Pain ... disease must be ... necrosis, and Paget disease ... #Pain #MSK #rheumatology ... approach #workup #differential
Sickle Cell Disease - Pathophysiology of disease and complications 

Due to the deformed shape, HbS induces
Sickle Cell Disease ... organs leading to ischemia ... , necrosis and pain ... #SickleCell #Disease ... Complications #Hematology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Pain - Diagnostic ... ), RA, crystal disease ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup #differential
Vascular Joint Pain - Differential Diagnosis Algorithm 
 - Constant Pain (Ischemia)
 - Acute Onset
 -
Vascular Joint Pain ... - Differential ... (Ischemia) - ... Peripheral Vascular Disease ... JointPain #MSK #Differential
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Pain Eyes ... polychondritis, GPA • Ischemic ... , Vasculitis (e.g ... #pain #differential ... #diagnosis #rheumatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Clinical features ... Alcohol-induced pain ... : Pain in involved ... involvement Differential ... #hematology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Differential Diagnosis ... - Autoimmune Rheumatologic ... Disease OLIGOARTHRITIS ... #pain #Differential ... Diagnosis #MSK #rheumatology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Clinical Features ... Diagnosis: • A clinical ... antiinflammatory properties e.g ... osteoarticular and skin disease ... SAPHO #Syndrome #Rheumatology