28 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
) Clinical Manifestations ... Cerebrovascular Disease ... #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis #management
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
in Sickle Cell Disease ... • Mechanism: ischemic ... dz difficult to see ... #Joint #Pain #SickleCell ... #Disease #differential
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
polychondritis, GPA • Ischemic ... Neurologic system ... Vasculitis (e.g. ... #joint #pain #differential ... #diagnosis #rheumatology
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Hematologic • Anemia ... Arthritis • SLE ... Obstructive Pulmonary Disease ... Neurologic • ... • Drug Abuse (e.g
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... function test, ANA (e.g ... ., SLE), anti-phospholipid ... (CVID, WAS), (neurologic ... changes), high MCV anemia
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... ) Differential Diagnosis ... retinal tears, Ischemia ... Syndrome #diagnosis #management ... signs #symptoms #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... permanent alopecia Differential ... Non-autoimmune rheumatologic ... lymphoproliferative syndrome Clinical ... lymphopenia, low PLT • Anemia
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... the presence of anemia ... (e.g., polymyalgia ... ANA and RF (if clinical ... diagnosis #testing #Rheumatology
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
intrinsic factor, IF) Clinical ... hypoxia and organ ischemia ... (e.g. ... to IBD, celiac disease ... Deficiency #diagnosis #management
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... , such as SLE, atherosclerotic ... affects the skin, neurologic ... cognitive impairment, neurologic ... #Diagnosis #Rheumatology