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diagnosis differential hyperkalemia management potassium high hydroxychloroquine lupus adverseeffects benefits classification k levels measurement risks serum sideeffects sjogrens sle syndrome
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
half-life = 40 days ([HCQI ... (e.g. renal failure ... Hydroxychloroquine #HCQ ... Measurement #SLE #rheumatology ... #pharmacology #
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
burns, trauma - Ischemic ... - Metabolic acidosis ... resistance Impaired Renal ... deficiency • Renal ... Type IV RTA • Renal
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
burns, trauma - Ischemic ... - Metabolic acidosis ... resistance Impaired Renal ... deficiency • Renal ... Type IV RTA • Renal
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
/crush injury, ischemia ... post-hypothermia • ↓ Renal ... Excretion: - Renal ... 15 suggests ↓ renal ... Treatment #potassium #nephrology
Hydroxychloroquine - Risks and Benefits in Lupus Benefits: ↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
rare with ~100 cases ... of renal or hepatic ... Hydroxychloroquine #hcq ... Benefits #Lupus #pharmacology ... #sideeffects #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
: • Purpura, ischemic ... pulmonary and renal ... tract, and often causes ... • Urinalysis (Renal ... differential #diagnosis #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
cirrhosis: 3%-20% Renal ... Distal (Type I) renal ... tubular acidosis ... lubricants • Pharmacologic ... Sjogrens #Syndrome #Rheumatology
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