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diagnosis differential rheumatology hemophagocytic hlh injury liver lymphohistiocytosis treatment aion anteriorischemicopticneuropathy apml cardiology clinical criticalcare cryofibrinogenemia differentiation foamed gca giantcellarteritis
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... fever - ACS, AKI ... , acute limb ischemia ... WBC >100k, + lab signs ... #hematology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... obstruction, HELLP Syndrome ... Budd-Chiari, Congestion/CHF ... #Acute #algorithm ... #hepatology
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA) 1) Is visual loss caused
Anterior ischemic ... Definition: acute ... ischemic disorder ... Doppler US : halo sign ... Ophthalmology #Diagnosis #Algorithm
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Diagnosis: >3 symptoms ... sepsis), PE, DAH, CHF ... APML #diagnosis #management ... #hematology #oncology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... Vascular Causes ... vein: Budd-chiari syndrome ... , Congestion/CHF ... #hepatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... Diagnosis: HLH signs ... and symptoms can ... presents as an acute ... #treatment #hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cryofibrinogenemia Symptoms ... limb and bowel ischemia ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... #hematology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
coronary syndrome ... the determined cause ... #differential #algorithm ... #management #cardiology ... #heartfailure #chf
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... purpura: Strong sign ... • Progressive symptoms ... Cerebrospinal fluid (CSF ... tract, and often causes
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... caused by uncontrolled ... Presentation • Common Signs ... and Symptoms: ... #Hematology #HemeOnc
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