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diagnosis management hematology differential hemophagocytic hlh lymphohistiocytosis neurology oncology vasculitis anemia behcet cerebritis chronic classification cll cns erythematosus hemeonc leukemia
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Anemia Clinical ... - Hepatitis, eosinophilic ... anemia Treatment ... Anemia #oncology #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... Cerebrovascular Disease ... that will cause ischemia ... CNS #neurology #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
(Clinical Dx). ... retinal tears, Ischemia ... Arthritis, AS Treatment ... diagnosis #management #signs ... #symptoms #rheumatology
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neurodegenerative disease ... • Or brainstem syndromes ... patients with clinically ... stimulation Clinical ... Multiple Sclerosis Treatment
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis: • Purpura, ischemic ... purpura: Strong sign ... progressive) EGPA (Eosinophilic ... Polyangiitis): • Eosinophilia ... Differential #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
: • Purpura, ischemic ... • EGPA: - Eosinophilia ... Kidneys: glomerular ischemia ... purpura: strong sign ... differential #diagnosis #rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Physical Exam/Signs ... cells can indicate disease ... Pure red cell aplasia ... microglobulin Treatment
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... age, however the disease ... Diagnosis: HLH signs ... #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... salivary ducts Clinical ... phenomenon (16%) MSK ... Adenocarcinoma Treatment ... #Rheumatology #
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
HLH is a critical ... ▪ Autoimmune diseases ... Clinical Presentation ... • Common Signs ... Diagnosis #Management #Hematology
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