12 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... autoantibodies that will cause ... ischemia and/or ... cyclophosphamide • Ischemic ... prevention (statin for CVA
Chronic Abdominal Pain Causes - Differential Diagnosis Framework

Many patients with chronic abdominal pain have had prior
Pain Causes - Differential ... • Colorectal CA ... mesenteric ischemia ... • Mesenteric ischemia ... #Chronic #Causes
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... Pain in Sickle ... • Mechanism: ischemic ... differential #diagnosis #causes ... #hematology
Sickle Cell Disease - Pathophysiology of disease and complications 

Due to the deformed shape, HbS induces
Cell Disease - Pathophysiology ... organs leading to ischemia ... , necrosis and pain ... SickleCell #Disease #Pathophysiology ... Complications #Hematology
Small Bowel Infarction - Pathogenesis and Clinical Findings

Thankfully, bowel infarction in general is the rarest cause
is the rarest cause ... acute abdominal pain ... colon is reduced, colonic ... to suffer from ischemia ... SmallBowel #Infarction #pathophysiology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... visual changes, stroke ... AKI, acute limb ischemia ... diagnosis #management #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Nephrotic Syndrome, Ischemic ... considered in all cases ... coagulation and other causes ... Venous #Arterial #pathophysiology ... #hematology #differential
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis: • Purpura, ischemic ... and mesenteric ischemia ... Non-glomerular ischemia ... Eosinophilia, asthma, chronic ... tract, and often causes
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
: • Purpura, ischemic ... Eosinophilia, asthma, chronic ... tract, and often causes ... Kidneys: glomerular ischemia ... Palpable purpura: strong
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Related conditions: Stroke ... limb and bowel ischemia ... cryoglobulins • Negative causes ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology