22 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Cerebrovascular Disease ... autoantibodies that will cause ... ischemia and/or ... cyclophosphamide • Ischemic ... CNS #neurology #rheumatology
Bradycardia Diagnostic and Management Algorithm

CONSIDER ETIOLOGY (not inclusive): 
 - STRUCTURAL: sick sinus, AV block, ischemia,
sinus, AV block, ischemia ... lyme + tick bome diseases ... LIFE THREATENING CAUSES ... & TREATMENT - ... euglycemia - Ischemia
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA)

1) Is visual loss caused
Anterior ischemic ... Definition: acute ischemic ... GiantCellArteritis #GCA #Rheumatology ... #Ophthalmology ... #Diagnosis #Algorithm
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Differential Diagnosis Algorithm ... Drugs/Toxins • Ischemia ... • Cholestatic disease ... Common Bile Duct Stone ... #Causes
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... Differential Diagnosis Algorithm ... disorders • Celiac disease ... effect following treatment ... #Causes #Hematology
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... in Sickle Cell Disease ... • Mechanism: ischemic ... Pain #SickleCell #Disease ... #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... visual changes, stroke ... AKI, acute limb ischemia ... organ damage • Treatment ... diagnosis #management #hematology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Related conditions: Stroke ... limb and bowel ischemia ... cryoglobulins • Negative causes ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Treatment of giant cell arteritis (GCA)

1st Line Strategy - GC 0.7 mg/kg/day, except for:
 • Aortitis
Treatment of giant ... mg/kg/day • Ischemic ... scalp necrosis, stroke ... MTX or TCZ in case ... #Indications #rheumatology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Algorithm - Approach ... nervous system (stroke ... impairment), heart disease ... , extremities (ischemia ... Nephrocalcinosis causes