29 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... autoantibodies that will cause ... ischemia and/or ... cyclophosphamide • Ischemic ... CNS #neurology #rheumatology
Diabetic Retinopathy: Pathogenesis and clinical findings

Mild Non-proliferative DR
 • Outpouchings of the weakened capillary walls or
re-vascularize the ischemic ... significant retinal ischemia ... Localized retinal ischemia ... #complications ... #pathophysiology
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
fluffy white ischemic ... Elschnig's Spots • Ischemia ... ophthalmology #diagnosis ... #signs #symptoms ... #complications
Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal
Anaphylaxis: Signs ... / Symptoms / Complications ... e.g. arrythmias, ischemia ... #Anaphylaxis #pathophysiology ... #immunology #diagnosis
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism

In contrast to the
from Myocardial Ischemia ... from myocardial ischemia ... associated with rheumatologic ... life-threatening causes ... #Diagnosis
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA)

1) Is visual loss caused
Anterior ischemic ... Definition: acute ischemic ... Doppler US : halo sign ... GiantCellArteritis #GCA #Rheumatology ... Ophthalmology #Diagnosis
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... AKI, acute limb ischemia ... WBC >100k, + lab signs ... Syndrome #TLS #diagnosis
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... • Mechanism: ischemic ... other orthopedic complications ... #differential #diagnosis ... #causes #hematology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
- Differential Diagnosis ... Dermatomyositis) AKI - Pathophysiology ... decreased renal renal ischemia ... Management #Summary #causes ... #treatment
Compartment Syndrome Pearls
A vicious cycle of increased pressure within a facial compartment leading to compression of
Pathophysiology: ... Tissue hypoxia → Ischemia ... Ischemic injury ... after the onset of ischemia ... Treatment: • Elevate