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management differential algorithm cardiology hematology pathophysiology signs syndrome symptoms criticalcare fungal hepatitis lfts nephrology rheumatology table ascites gastroenterology infectiousdiseases injury
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
> 50x normal - Ischemic ... > 20x normal - Acute ... CMV), Alcoholic cirrhosis ... AST:ALT = 1 - Ischemia ... Viral Hepatitis, Ischemic
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
Causes of Severe ... Acute Liver Injury ... - Ichemic hepatitis ... - Drug-Induced liver ... #Hepatology #Diagnosis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
- Differential Diagnosis ... • NAFLD • Cirrhosis ... Hepatopathy • Acute ... injury) • Ischemic ... #hepatology #transaminitis
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... ACLF) Clinical Guidelines ... months without treatment ... #Hepatology #gastroenterology ... #management #diagnosis
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Drugs/Toxins • Ischemia ... Infiltrative • Cirrhosis ... Others #LFTs #Hepatology ... #Algorithm #Causes
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
- Differential Diagnosis ... >10 mmHg - clinically ... /acute hepatitis ... sarcoidosis) • Liver ... #causes #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... for alternative causes ... disease, Hepatic ischaemia ... dechallenge • Acute ... #Algorithm #hepatology
Diffuse Acute Abdominal Pain (<72 hours) - Differential Diagnostic Algorithm Look for surgical abdomen Upper quadrant: R/O cardiac,
Diffuse Acute Abdominal ... - Differential Diagnostic ... : R/O cardiac, pulmonary ... musculoskeletal causes ... • Mesenteric ischemia
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... autoantibodies that will cause ... ischemia and/or ... permeability Diagnosis ... cyclophosphamide • Ischemic
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... - Differential Diagnosis ... Drugs, Viral, Ischemia ... Congenital, Others, Cirrhosis ... #hepatology #LiverFunctionTests
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