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diagnosis algorithm liver management lfts transaminitis peds disease hepatitis nephrology pathophysiology pulmonary rhabdomyolysis syndrome thrombosis abnormal abscess acidosis acute air
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
> 50x normal - Ischemic ... CMV), Alcoholic cirrhosis ... AST:ALT = 1 - Ischemia ... Viral Hepatitis, Ischemic ... #hepatology #LFTs
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
Causes of Severe ... Acute Liver Injury ... - Ichemic hepatitis ... #Differential # ... Hepatology #Diagnosis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Tests (LFTs) - Differential ... • NAFLD • Cirrhosis ... Drug-induced liver injury ... ) • Ischemic Hepatopathy ... #Diagnosis #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Liver Enzymes - Differential ... Drugs/Toxins • Ischemia ... Infiltrative • Cirrhosis ... Others #LFTs #Hepatology ... Diagnosis #Algorithm #Causes
Portal Vein Thrombosis (PVT) Treatment Algorithm - If concern for ischemic: anti-coag+multidisciplinary care - W/o cirrhosis+recent
If concern for ischemic ... multidisciplinary care - W/o cirrhosis ... anti-thrombotic tx - Cirrhosis ... : case-by-cased ... management #Algorithm #hepatology
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
Rhabdomyolysis - Differential ... decreased renal renal ischemia ... Treatment: 1 ... Management #Summary #causes ... #treatment
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
- Differential ... Differential Diagnosis ... • Vascular: Ischemic ... #Differential # ... Diagnosis #hepatology
Causes of Biliary Dilatation - Differential Diagnosis • Physiological: ↑ Age, Cholecystectomy, Opioid dependence, Post-sphincterotomy •
Causes of Biliary ... Dilatation - Differential ... Parasitic infection, Ischaemic ... #differential # ... diagnosis #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Function Tests - Differential ... Drugs, Viral, Ischemia ... Congenital, Others, Cirrhosis ... Algorithm #diagnosis #hepatology
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... • Mechanism: ischemic ... • Differentiate ... #diagnosis #causes ... #hematology
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