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diagnosis differential management algorithm hematology cardiology gastroenterology injury lfts nephrology transaminitis rheumatology abdominal ascites clinical elevated pain abnormal aki albumin
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
> 50x normal - Ischemic ... > 20x normal - Acute ... CMV), Alcoholic cirrhosis ... AST:ALT = 1 - Ischemia ... Viral Hepatitis, Ischemic
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
Causes of Severe ... Acute Liver Injury ... - Ichemic hepatitis ... - Drug-Induced liver ... #Hepatology #Diagnosis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Elevated Liver Function ... • NAFLD • Cirrhosis ... Hepatopathy • Acute ... injury) • Ischemic ... Differential #Diagnosis #hepatology
Mesenteric Ischemia - Differential Diagnostic Schema Chronic: ASCVD, Venous, Vasculitides 5% (PAN, [E]GPA, IgA, MPA) Acute - Venous
Mesenteric Ischemia ... GPA, IgA, MPA) Acute ... Antiphospholipid syndrome ... hypovolemia), Meds/Treatments ... #Mesenteric #Ischemia
Indications for Albumin for Management of Cirrhosis • Large volume paracentesis (>5 liter) - 8g per
Management of Cirrhosis ... ascites removed • Acute ... • Hepatorenal syndrome ... Indications #Management #Cirrhosis ... #treatment #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... those with CLD (± cirrhosis ... months without treatment ... #Failure #Cirrhosis ... #Hepatology #gastroenterology
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
and hepatorenal syndrome ... Clues to non-cirrhotic ... /acute hepatitis ... sarcoidosis) • Liver ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Drugs/Toxins • Ischemia ... Infiltrative • Cirrhosis ... Others #LFTs #Hepatology ... Diagnosis #Algorithm #Causes
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
Etiologies of Cirrhosis ... Nonalcoholic fatty liver ... disease (Budd-Chiari syndrome ... #Differential #Hepatology ... #Cirrhosis #Causes
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 Causes of Ascites - Differential Diagnosis Algorithm Portal Hypertension - Prehepatic: • Portal vein thrombosis • Splenic
Causes of Ascites ... - Hepatic: • Cirrhosis ... Infiltrative disease • Acute ... liver failure ... Diagnosis #Algorithm #Hepatology
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