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diagnosis differential management hematology algorithm thrombosis arterial cerebritis classification cns cryofibrinogenemia embolism erythematosus leukostasis liverenzymes lupus lysis neurology pathophysiology portalvein
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Drugs/Toxins • Ischemia ... Infiltrative • Cirrhosis ... • Others #LFTs ... #Hepatology #LiverEnzymes ... Diagnosis #Algorithm #Causes
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... autoantibodies that will cause ... ischemia and/or ... cyclophosphamide • Ischemic ... CNS #neurology #rheumatology
Portal Vein Thrombosis (PVT) Treatment Algorithm - If concern for ischemic: anti-coag+multidisciplinary care - W/o cirrhosis+recent
If concern for ischemic ... multidisciplinary care - W/o cirrhosis ... anti-thrombotic tx - Cirrhosis ... : case-by-cased ... management #Algorithm #hepatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... AKI, acute limb ischemia ... organ damage • Treatment ... Low calcium • Treatment ... diagnosis #management #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
• Nephrotic Syndrome ... , Ischemic Liver ... considered in all cases ... coagulation and other causes ... pathophysiology #hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
limb and bowel ischemia ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal Syndromes ... EGPA) • Digital ischemia ... pericardial effusion) • PFTs ... Goodpasture's cause ... diagnosis #management #treatment
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
: • Purpura, ischemic ... tract, and often causes ... Kidneys: glomerular ischemia ... Tests: • CBC • LFT ... differential #diagnosis #rheumatology
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