11 results
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
> 50x normal - Ischemic ... 20x normal - Acute ... AST:ALT = 1 - Ischemia ... , Ischemic Necrosis ... #Injury #hepatology
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
Liver Injury ... - Ichemic hepatitis ... - Drug-Induced liver ... #Differential #Hepatology ... #Diagnosis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
- Differential Diagnosis ... Hepatopathy • Acute ... Viral Hepatitis ... injury) • Ischemic ... #hepatology #transaminitis
ISCHEMIA Trial - Management Algorithm for patients with Stable Angina

Stress Test -> ? +moderate or severe
ISCHEMIA Trial - ... moderate or severe ischemia ... This is not for acute ... on results of ISCHEMIA ... /alenghat/ #ISCHEMIA
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... disease, Hepatic ischaemia ... dechallenge • Acute ... #Injury #Diagnosis ... #Algorithm #hepatology
Clinical Diagnosis of Autoimmune Hepatitis
 - Onset of jaundice within prior 8 weeks
 - Ongoing consumption
Clinical Diagnosis ... factors - Possible ischemic ... hepatitis (e.g. ... ) or metabolic liver ... #Diagnosis #Hepatology
Clinical diagnosis of Alcoholic Hepatitis (AH)
 • Onset of jaundice within prior 8 weeks
 • Ongoing
Clinical diagnosis ... factors • Possible ischemic ... hepatitis (e.g. ... ) or metabolic liver ... #hepatology #criteria
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis
High albumin gradient (>1.1 g/dl):
 - Cirrhosis	
 - Alcoholic
- Differential Diagnosis ... - Alcoholic hepatitis ... Veno-occlusive disease - Acute ... associated with bowel ischemia ... #hepatology
Severe Heart Failure & Cardiogenic Shock - Management Checklist 
Evaluation 
 - EKG & echocardiography
Lytes including Ca ... Troponin, Lactate, Liver ... drained if causing acute ... antiarrhythmics - Ischemic ... #HeartFailure #Cardiology
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Culture (+): Acute ... Early embolic/ischemic ... Differential Diagnosis ... ↑ ESR, CRP • EKG ... #management #cardiology