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differential management liver injury oncology rheumatology anemia classification gastroenterology lfts transaminitis nephrology ophthalmology pain pathophysiology aki alcoholic ascites cardiology chronic
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
> 50x normal - Ischemic ... 20x normal - Acute ... AST:ALT = 1 - Ischemia ... , Ischemic Necrosis ... Liver #Injury #hepatology
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
Causes of Severe ... Acute Liver Injury ... - Ichemic hepatitis ... #Causes #Differential ... #Hepatology #Diagnosis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
- Differential Diagnosis ... Hepatopathy • Acute ... Viral Hepatitis ... liver injury) • Ischemic ... #hepatology #transaminitis
Hepatitis B Virus Serology and Interpretation HBsAg - Anti-HBs - Anti-HBc - HBeAg - Anti-HBe - Acute
- Anti-HBe - Acute ... (about 10% of cases ... ) - Acute hepatitis ... Interpretation #diagnosis ... #laboratory #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Algorithm Severe ... Drugs/Toxins • Ischemia ... • Alcoholic hepatitis ... Others #LFTs #Hepatology ... #Algorithm #Causes
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Infectious: • Acute ... effect following treatment ... #Algorithm #Causes ... #Hematology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... for alternative causes ... disease, Hepatic ischaemia ... dechallenge • Acute ... #Algorithm #hepatology
Mesenteric Ischemia - Differential Diagnostic Schema Chronic: ASCVD, Venous, Vasculitides 5% (PAN, [E]GPA, IgA, MPA) Acute - Venous
Mesenteric Ischemia ... GPA, IgA, MPA) Acute ... hypovolemia), Meds/Treatments ... #Mesenteric #Ischemia ... #Diagnosis #algorithm
Initial triage of the neutropenic adult - Algorithm for the evaluation and treatment of adult patients
neutropenic adult - Algorithm ... evaluation and treatment ... #neutropenia #Algorithm ... #workup #diagnosis ... #hematology #biopsy
Acute Diarrhea - Differential Diagnosis Algorithm • Ischemic: Small Bowel vs Large Bowel • Infectious: Diarrhea-Predominant
Acute Diarrhea - ... Differential Diagnosis ... Algorithm • Ischemic ... Diarrhea-Predominant vs Nausea ... #Algorithm
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