14 results
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
> 50x normal - Ischemic ... > 20x normal - Acute ... AST:ALT = 1 - Ischemia ... , CHF AST:ALT ... Viral Hepatitis, Ischemic
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Elevated Lactate ... Legionnaires disease • Pulmonary ... hepatitis • Ischemic ... distinguishes ischemic ... • Demand ischemia
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Medications, Spinal Cord Injury ... Decompensated CHF ... • Obstructive: Pulmonary ... ) UOP > 0.5 cc/kg ... #criticalcare #
Approach to Possible Hypertensive Emergency

criteria required to diagnose hypertensive emergency
(1) Severe hypertension
 - Usually a MAP
kidney injury ( ... - Myocardial ischemia ... type-II myocardial ischemia ... - Pulmonary edema ... #Algorithm #CriticalCare
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
, - regional ischemia ... liver or renal injury ... - regional ischemia ... pulmonary edema ... - Mesenteric ischemia
Noncardiogenic Pulmonary Edema - Differential Diagnosis Framework

NCPE Pathophysiology:
Noncardiogenic pulmonary edema occurs because of excessive pulmonary capillary
- Differential Diagnosis ... • A lack of acute ... level <100 pg/ml EKG ... • Negative for ischemic ... #differential #diagnosis
Severe Heart Failure & Cardiogenic Shock - Management Checklist 
Evaluation 
 - EKG & echocardiography
- Troponin, Lactate ... drained if causing acute ... antiarrhythmics - Ischemic ... treatment for acute ... #Checklist #CHF
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... disease, Hepatic ischaemia ... dechallenge • Acute ... #Diagnosis #Algorithm ... #hepatology
Shock - Diagnosis and Management Summary
 • Hypotension: SBP<90, SBP drop >40, MAP<65 (Normotension, HTN possible
) • Elevated lactate ... telemetry, 12-Lead EKG ... Tamponade - Pulmonary ... >> Acute PE, Tension ... Management #Summary #criticalcare
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
EGPA) • Digital ischemia ... mononeuritis multiplex WORKUP ... & DIAGNOSIS Labs ... quantify renal injury ... recent DAN) • EMG