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diagnosis algorithm rheumatology treatment transaminitis classification liver oncology pulmonary workup acute cardiology disease dyspnea elevated endocarditis hepatitis injury mds myelodysplastic
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
> 50x normal - Ischemic ... AST:ALT = 1 - Ischemia ... Viral Hepatitis, Ischemic ... Liver #Injury #hepatology ... #differential #
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Function Tests (LFTs ... ) - Differential ... liver injury) • Ischemic ... #Differential # ... Diagnosis #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Liver Enzymes - Differential ... Drugs/Toxins • Ischemia ... • Others #LFTs ... #Hepatology #LiverEnzymes ... Diagnosis #Algorithm #Causes
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
Causes of Severe ... Liver Injury - Ichemic ... Severe #Acute #Causes ... #Differential # ... Hepatology #Diagnosis
Causes of Biliary Dilatation - Differential Diagnosis • Physiological: ↑ Age, Cholecystectomy, Opioid dependence, Post-sphincterotomy •
Causes of Biliary ... Dilatation - Differential ... sludge), Mirizzi's syndrome ... Parasitic infection, Ischaemic ... diagnosis #hepatology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential ... Megakaryopoiesis • Aplastic Anemia ... Non-lmmune: • HELLP Syndrome ... #Hematology
Diffuse Acute Abdominal Pain (<72 hours) - Differential Diagnostic Algorithm Look for surgical abdomen Upper quadrant: R/O cardiac,
(<72 hours) - Differential ... musculoskeletal causes ... • Mesenteric ischemia ... • Sickle cell anemia ... Irritable bowel syndrome
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
Dyspnea - Differential ... Hepatopulmonary syndrome ... Transverse myelitis • Hematology ... : - Anemia • ... #dyspnea #sob #differential
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... - Differential ... malignancies • Anemia ... Myelodysplastic syndrome ... #hematology #secondary
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Function Tests - Differential ... Drugs, Viral, Ischemia ... Burak @kwburak #LFTs ... Algorithm #diagnosis #hepatology
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