9 results
Validation of the Step-By-Step Approach to Febrile Infants

#Diagnosis #Management #Pediatrics #Peds #Febrile #Infant #StepByStep #Algorithm #LP
#Diagnosis #Management ... #Pediatrics #Peds ... Algorithm #LP #Antibiotics ... #Risk #Stratification ... #Fever #RebelEM
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... #Diagnosis #Management ... #Pediatrics #Peds ... #Febrile #Infant ... Algorithm #LP #Antibiotics
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... AKI, acute limb ischemia ... : - If febrile ... TLS #diagnosis #management ... #hematology
The Febrile Infant Step-by-Step Algorithm
This is an algorithm developed by European emergency physicians to identify low-risk
The Febrile Infant ... treatment. http ... Diagnosis #EBM #Management ... #Pediatrics #Peds ... #Fever
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
acute or subacute febrile ... following: • Fever ... rapidly, and empiric antibiotic ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
patients with minimal tumor ... ) B symptoms → fevers ... chemotherapy for low-risk ... Leukemia #oncology #hematology ... hemeonc #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Attempt if high risk ... Subacute-Acute: • Common: fever ... Rare: DAH, acute febrile ... APML #diagnosis #management ... #hematology #oncology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
work-up - If febrile ... 500 → may stop antibiotics ... TLS (tumor-lysis ... syndrome): - Hematologic ... mg/dL or > 25 % rise
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma Risk ... • Dyspnea • Fever ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management