307 results
Antifungal Azoles - Antibiotics Class Overview

Mechanism:  inhibit ergosterol synthesis (important component of fungal cell membranes)
Antifungal Azoles ... important component of fungal ... Itraconazole has ... Itraconazole(PO ... Overview #Azoles #Antifungal
Antifungal Coverage Activity Antibiogram 

Spectrum of action of systemic antifungal agents. Solid blocks represent species in
Antifungal Coverage ... action of systemic antifungal ... species in which the antifungal ... lines indicate fungal ... fluconazole; ITRA = itraconazole
Majocchi’s Granuloma due to Trichophyton rubrum 
This is GMS stain and culture of a skin biopsy
Histopath shows fungal ... Treatment: Itraconazole ... : terbinafine, Itraconazole ... : Terbinafine, Itraconazole ... Rx: Oral antifungal
Moccasin-variety Tinea Pedis 
70 M chronic scaly feet. Over the years: rash has itched only occasionally;
Topical anti fungal ... requiring oral antifungal ... with terbinafine, itraconazole
Spectrum of activity for systemic antifungal agents
Antifungals: 5FC, flucytosine; AMB, amphotericin B; ANI, anidulafungin; CAS, caspofungin;
activity for systemic antifungal ... agents Antifungals ... isavuconazole; ITR, itraconazole ... .2015.10.012 #Antifungal
Antifungal Agents Frequently Used in Leukemia
Antibiogram:
 • Fluconazole
 • Itraconazole
 • Voriconazole
 • Posaconazole
 • Caspofungin
Antifungal Agents ... Fluconazole • Itraconazole ... @ZhuoerXie #Antifungal
Tinea Versicolor (Pityriasis versicolor) 
NOT a dermatophyte infection 
Caused by saprophytic, lipid-dependent yeasts 
Clinical 
 •
Management • Topical antifungals ... • Oral antifungal
Antifungal Polyenes - Amphoterecin B, Abelcet, Ambisome - Antibiotics Class Overview

Mechanism: binds ergosterol in membrane and
Antifungal Polyenes ... for many severe fungal ... Overview #Polyenes #Antifungal
Important Fungal Stains
Mycology Lab:
 • Calcofluor white - Fluorochrome that binds glucans and chitin in fungal
Important Fungal ... and chitin in fungal ... visualization of fungal ... cell response to fungi ... #Fungal #Stains
Common Medications Known to Prolong QTc
Antiarrhythmics - Amiodarone, sotalol, flecainide, quinidine, dronedarone, dofetilide
Vasopressors/inotropes - Epinephrine, norepinephrine,
promethazine Antifungals ... - Fluconazole, itraconazole